Introduction for Isorhamnetin benefits
Isorhamnetin benefits are the main active ingredient of flavonoids in oriental stalk. Sarcopyramis bodinieri var. Delicata belongs to Melastomata-ceae, which is mainly distributed in Jiangxi, Fujian and Taiwan. Oriental fleshy grass is medicinal, with liver, spleen and stomach. It has the effects of clearing away heat and detoxifying, clearing liver and purging fire. It is used to treat acute hepatitis, lung heat cough, snake head mites, nameless swollen poison, gastroenteritis and other diseases. The rare and precious Chinese medicines are widely used in Jiangxi and Longnan.
Free radicals mainly include various forms of active oxygen, which are active in nature and extremely oxidizing, which is very harmful to humans. Free radicals can oxidize, modify, and even break DNA; free radicals can oxidize proteins and enzyme sulfhydryl groups, changing their structure and function; free radicals can also oxidize highly unsaturated fatty acids in cell membrane phospholipid molecules to form lipid peroxides, causing organisms Membrane damage. Tissue cell aging is also closely related to increased free radicals in the body.
In vitro hepatic mitochondrial lipid peroxidation, Isorhamnetin benefits is a good model for studying the antioxidant activity of substances. In vitro hepatic mitochondrial lipid peroxidation was initiated by Fe2 + /Vc system. The most important stable product of lipid peroxidation was malondialdehyde MDA, which was colored by MDA with thiobarbituric acid (TBA) (product is TBARS). The amount of TBARS is determined to indicate the extent of lipid peroxidation.
The experimental results show that isorhamnetin has obvious antioxidant activity and concentration-dependent effect. In the DPPH free radical scavenging, ABTS free radical scavenging and inhibition of liver mitochondrial lipid peroxidation test, the final concentration of isorhamnetin IC50 is 32, 14. 54, 6. 67 μmol/L. Isorhamnetin benefits have a stronger ability to scavenge DPPH free radicals and clear ABTS free radicals, and will make a lot of achievements in food additives in the future.
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