Genistein is one of the main active factors in soybean isoflavones. It is the most effective functional ingredient in soybean isoflavones, and has many physiological functions. Genistein is structurally similar to estrogen - estradiol in mammals, with the active group of estrogen - two phenolic hydroxyl groups, so genistein has many physiological activities like estrogen like activity.
Molecular formula: C15H10O5
Prevention of osteoporosis
Osteoporosis is the reduction of phalangeal tissue, resulting in brittle bones and fragile bones. It is commonly seen in women after menopause and in elderly men (due to hormonal changes or deficiency of calcium and vitamin D). The incidence of osteoporosis in middle-aged and old women is much higher than that of men. The main reason is the decrease of estrogen level after the ovarian function decline, the negative balance of bone metabolism and the decrease of bone mass. Isoflavones can bind to estrogen receptors on bone cells, reduce bone loss, increase body absorption of calcium and increase bone density.
In women's menopause, due to the decline of ovarian function, the level of estrogen in the body drops, the functional adjustment of organs and tissues is not adapted to a series of diseases, and supplemental estrogen can achieve the purpose of preventing and treating such diseases.
The performance of women menopause: hot flashes, sweats, chills, chest tightness, palpitations, shortness of breath, dizziness, blood pressure fluctuations, etc.; emotional instability, irritability, agitation or depression, anxiety, insomnia, memory impairment, lack of thought and comprehensive judgment.
Prevention of breast cancer
Taking estrogen alone for a long time can increase the incidence of breast cancer and endometrial cancer by 5 to 7 times. The structure of soybean isoflavone is similar to that of estrogen, so it can combine the female receptor on the surface of the cell and activate the other anticancer mechanism, which reduces the risk of women with endometrial cancer and breast cancer at the high level of estrogen.
Soybean products contain 5 known anticancer factors, one of which is phytoestrogen (isoflavone), which is the unique anticancer factor of soybean food. Scientists concluded that the antioxidation and genoprotective effect of genistein is the main cause of its anticancer effect. Soybean isoflavones have obvious therapeutic effects on breast cancer, colon cancer, lung cancer, prostate cancer, skin cancer and leukemia, and soybean isoflavones can also prevent the occurrence of ovarian, colon, gastric and prostate cancer.
A large number of studies have found that soy isoflavones can convert cancer cells into normal functioning cells, and also inhibit the structure of bad mass, prevent mass proliferation and cancer cell proliferation.
Prevention of disease
Heart disease is also a disease associated with estrogen. As a plant estrogens, soy isoflavones can reduce blood lipids and prevent heart disease: estrogen like action promotes thyroxine secretion and promotes bile excretion. Lowering cholesterol lowers low density lipoprotein (LDL) cholesterol without reducing the high density lipoprotein (HDL) cholesterol, which has been fully demonstrated. Isoflavones, as the characteristics of flavonoids, have biological antioxidant effects, which is very important. Because the oxidation of low density lipoprotein (LDL) cholesterol is a key factor in the process of atherosclerosis. Women who receive 80 mg of genistein daily can increase arterial elasticity by about 26%.
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