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Coenzyme Q10 function
Jul 25, 2017

Q10

Coenzyme Q10, also known as ubiquinone, is a fat soluble quinone in nature. Its structure is similar to vitamin K, vitamin E and plastid quinone. Participation in energy production and activation in the human body cells is the most effective antioxidation component in the prevention of arteriosclerosis.

 

The quinone structure in the molecule makes ubiquinone have two forms: oxidized (ubiquinone, Coenzyme Q10) and reductive (phenol, Ubiquinol). These two forms can be interchanged in cells, which is the basis of ubiquinone as electron transport body. The electron gain of ubiquinone can be carried out in two steps, that is, one electron is transferred at one time, and one step can be carried out at the same time, and two electrons are transferred simultaneously.

 

Ubiquinone exists in most eukaryotic cells, especially mitochondria. It is one of the respiratory chain components. Its content in the mitochondrial inner membrane is much higher than that of other components in the respiratory chain, and its liposoluble makes it highly fluidity on the inner membrane, so it is especially suitable for being a flowing electron transport body.

 

The quinone part of ubiquinone is synthesized in the body with tyrosine, while the isoprene side chain is synthesized from acetyl CoA via methalolate pathway. Therefore, the beta blocker and cholesterol lowering statin, which play a role in blocking mevalate pathway, also affect the ubiquinone synthesis in vivo.

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Coenzyme Q10 (CoQ10) is a substance that helps convert food into energy. CoQ10 is found in almost every cell in the body, and it is a powerful antioxidant.

 

Antioxidants fight damaging particles in the body known as free radicals, which damage cell membranes, tamper with DNA, and even cause cell death. Scientists believe free radicals contribute to the aging process, as well as a number of health problems, including heart disease and cancer. Antioxidants, such as CoQ10, can neutralize free radicals and may reduce or even help prevent some of the damage they cause.

 

Some researchers believe that CoQ10 may help with heart-related conditions, because it can improve energy production in cells, prevent blood clot formation, and act as an antioxidant.


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