The intestine is the longest organ in the human body and an important part of the digestive system. It is responsible for the digestion and absorption of the ingested food. At the same time, the intestines are also part of the body's defenses and are responsible for protecting the health of the body. The intestine itself also needs protection to prevent bacterial invasion and prevent inflammation. Recent studies have shown that Astragalus membranaceus extract can prevent intestinal mucosal damage by reducing inflammation.
Gram-negative bacteria can trigger the immune system to release substances that promote inflammation through the lipopolysaccharide endotoxin in the cell wall. If not properly controlled, these cells produce excessive inflammatory factors, leading to systemic inflammation, thereby increasing the risk of other diseases.
"BMC Supplementary and Alternative Medicine" magazine evaluated the protective effect of Astragalus membranaceus extract on intestinal mucosal lipopolysaccharide damage in male ICR mice. The assessment is based on parameters such as the presence of pro-inflammatory cytokines and the pathological condition of the intestinal wall tissue. The researchers found that increased levels of pro-inflammatory cytokines in untreated mice suggest that lipopolysaccharide causes inflammation. The sputum levels of the mice treated with Astragalus membranaceus were similar to those of the control mice. It has been shown to prevent lipopolysaccharide-induced damage and does not trigger the body's immune response.