Silybin Phytosome

Silybin Phytosome

● a medicinal plant of the genus Milk Thistle
● clearing away heat and relieving poison
● the protection of liver function


Introduction for silybin phytosome

This Silybin phytosome is a medicinal plant of the genus Milk Thistle, which has the traditional effect of clearing away heat and relieving poison, soothing liver and gallbladder. The active ingredient obtained by extracting and refining the dried fruit of the milk thistle is called Silybin phytosome. In Europe and the United States, Silybin phytosome is a relatively classic liver-protecting drug and is widely used in the treatment of various liver injuries. In recent years, Silybin phytosome has been gradually used in the field of health foods, mainly for the protection of liver function. At present, the research on Silybin phytosome at home and abroad mainly focuses on its efficacy, and there are few reports on the evaluation of the safety of milk thistle.

Toxic test

Acute oral toxicity test 20 healthy SD rats, half male and half female, weighing 180-220 g, were treated with the maximum tolerated dose (MTD) method. Ames experiment Using the plate incorporation method, the qualified strains TA97, TA98, TA100, TA102 were used, and the S9 mixture was used as the in vitro metabolic activation system. In the mouse bone marrow polychromatic erythrocyte micronucleus test, 50 healthy Kunming mice, weighing 25 ~ 30g, were randomly divided into 5 groups, 10 in each group. The dose was designed according to the one-time maximum intragastric dose method. The three dose groups were 1.50, 3.00, 6.00g/kg·BW, and another solvent control group and cyclophosphamide positive control group (40mg/ Many methods such as kg·BW) are tested.

silybin phytosome

The acute oral tolerance (MTD) of Silybin phytosome to female and male rats was greater than 18.0g/kg·BW. The results of Ames test, mouse bone marrow micronucleus test and sperm abnormality test showed that the sample had mutagenic effect, and no obvious toxicity was observed in the 30d feeding experiment. Conclusion: The acute toxicity classification of milk thistle is non-toxic and non-genotoxic. Under the dose and conditions of this experiment, there is no obvious side effect of milk thistle.


Carton: 1kg with double plastic container inside/Aluminum foil bag outside; 

25kg with double plastic container inside/Fiber drum outside.

or as customer’s requirement.

Drum: 10kg,15kg,25kg




Shipping Terms

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Suitable for ≤50kgs


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Suitable for ≥500kgs


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Payment Terms

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Finishing workshop

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