Tranexamic Acid Function

Tranexamic Acid Function

● INCI Name : Tranexamic acid
● Synonyms : m-tranexamic acid
● Chemical Name : trans-4-(aminomethyl)cyclohexanecarboxylic acid
● CAS No. : 1197-18-8
● EINECS No. : 214-818-2

Details

Tranexemic acid is a competitive inhibitor of plasmin activation, commonly used as a hemostatic agent due to its anti-fibrinolysis action is also promoted as a systemic skin whitening agent particularly as oral or intradermal injections for melasma. Tranexamic acid has become a phenomenon in Malaysia as skin whitening and melasma therapy.


INCI Name : Tranexamic acid

Synonyms : m-tranexamic acid

Chemical Name : trans-4-(aminomethyl)cyclohexanecarboxylic acid

CAS No. :  1197-18-8

EINECS No. : 214-818-2


Melasma is a common acquired pigmentary disorder that occurs usually in women, especially in Asia. The prevalence of melasma is around 13% and can seriously affect the appearance and quality of life of the women it affects. Oral tranexamic acid (TXA) treatment is regarded as the preferred method for curing melasma in some countries. However, oral TXA treatment of melasma, which requires a long treatment period, has the side effect of menstrual reduction in some patients. Therefore, topical TXA treatment of melasma has received much more attention. Nowadays, TXA is added to some cosmetics。

 

Tranexamic acid is a kind of protease inhibitor. It rapidly suppresses the activity of tyrosinase and melanocytes. After its entry into the dermis, it increases collagen synthesis directly and thoroughly cuts off the channel for the formation of melanin due to ultraviolet irradiation. The special hypodermis absorbent it contains can rapidly and effectively whiten the skin. It helps eliminate black spots, prevents and reduces pigmentation, leaving the skin white and pretty.

Mechanism of whitening skin

  • Block melanin formation path induced by ultraviolet rays

  • Prevent melanin accumulation


Decreases melanocyte tyrosinase activity by preventing the binding of plasminogen to the

keratinocytes, which results in reduction of prostaglandins and arachidonic acid, which are

inflammatory mediators involved in melanogenesis.

 

Synergistic effects with other whitening ingredients

Tranexamic acid produces good synergistic effect when combined with ascorbic acid or its derivatives such as magnesium ascorbyl phosphate, 3-O-ethyl ascorbic acid, disodium adenosine triphophate, escinol (deacylated product of escin under hydrolysis by sodium methylate), L-cysteine. Penetration enhancers helps the transdermic absorption of tranexamic acid into spots.

Functions

1. Whitening and prevent pigmentation ~ Reduce or remove the pigmentation of skin ~ Prevent and/or treat pigmentations such as chloasmas, freckles, sunburn, dark skin and melanoderma caused by a drug such as steroid ~Minimize dark spot area due to sun exposure. ~ Anti-inflammation Act on the chronic mild inflammatory condition at the sites of spots, to suppress melanocyte activation

 

2. Inhibit or improve skin roughness  ~ Restore damaged skin caused by UVA/UVB, pollution or other environmental factors.

 

3. Mechanism of whitening skin  ~ Block melanin formation path induced by ultraviolet rays ~ Prevent melanin accumulation ~ Decreases melanocyte tyrosinase activity by preventing the binding of plasminogen to the keratinocytes, which results in reduction of prostaglandins and arachidonic acid, which are inflammatory mediators involved in melanogenesis.

Packing

Carton: 1kg with double plastic container inside/Aluminum foil bag outside; 

25kg with double plastic container inside/Fiber drum outside.

or as customer’s requirement.

Drum: 10kg,15kg,25kg

   


packaging.jpg

Delivery

Shipping Terms

By express

By Air

By Sea

Suitable for ≤50kgs

Faxter:5-7days

High cost

Door to Door

Easy Pick Up Goods

Suitable for ≥50kgs

Faster:1-2days

High Cost

Airport to Airport

Pick Up Goods by Customer

Suitable for ≥500kgs

Fast:15-30days

Low Cost

Port to Port

Pick Up Goods by Customer

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Payment:

 

Payment Terms

Western Union

Money Gram

Paypal

Bank Transfer

Finishing workshop

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Exhibition

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