Kojic acid, also known as Aspergillus acid, has a strong inhibitory effect on the formation of melanin in human skin, and is safe, non-toxic, and does not produce any sequela. Therefore, in the make-up water, mask, emulsion, cream, can effectively treat freckles, old age spots, pigmentation, acne cosmetics.Many products with kojic acid are intended for use on the hands or face.
Kojic acid is a colorless, tasteless, safe and effective tyrosinase inhibitor. It is a weak acid compound produced by aerobic fermentation of some strains of genus koji by using glucose, fructose, sorbitose and sugar alcohol. Kojic acid is colorless prism crystal, soluble in water, alcohol and acetone, slightly soluble in ether, ethyl acetate, chloroform and pyridine, and is insoluble in benzene.
The mechanism of freckle and whitening of kojic acid
Melanin is a naturally occurring pigment in the body that gives the eyes, hair, and skin their color. An amino acid called tyrosine is needed to support the production of melanin.
Kojic acid works by blocking tyrosine from forming, which then prevents melanin production. Decreased melanin production may have a lightening effect on the skin.
Color spots are usually brown non inflammatory pigmentation in the women's face after puberty. The cause of the disease is the hyperactivity of the melanocytes or the maladjustment of vitamins, which causes the increase of the black pigment in the upper part of the nucleus of the epidermis. Melanin in human epidermal cells is composed of tyrosine, tyrosinase, DOPA, DOPA and quinone. A part of its chemical structure is similar to hydroquinone and tyrosine, tyrosine, Doba, and Doba = quinones. The inhibition principle of melanin synthesis is that they bind to Cu ions in reaction, prevent the activation of tyrosinase from the copper ions, or have an impediment to the contention of the enzyme.
The benefits of using products containing kojic acid may include the following:
Anti-aging effect: Products containing kojic acid may lighten the skin, which can improve the appearance of age spots and sun damage. The reduction of dark spots can have an anti-aging effect.
Treat melasma: Kojic acid may also be helpful in decreasing melasma, which is darkening of the skin due to pregnancy.
Decrease the appearance of scars: Kojic acid may also reduce the discoloration of scars. Although the acid does not improve the thickness of scar tissue, it may reduce dark pigmentation associated with certain types of scars. Lightening the scar may make it less noticeable.
Antifungal benefits: Kojic acid is also thought to have some antifungal benefits. It may be helpful in preventing and treating certain fungal infections, such as athlete's foot and yeast infections.
Antibacterial effects: Kojic acid may also provide antibacterial benefits. It may help decrease the chances of developing common types of bacterial skin infections.
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