Glabridin is a chemical compound that is found in the root extract of licorice (Glycyrrhiza glabra). It is used as an ingredient in cosmetics with benefits of inhibiting tyrosinase, dopachrome tautomerase and activity of DHICA oxidation enzyme. It helps in the reduction of melanin synthesis, skin-tone lightening, and reduction of age-spots, as a smoothing agent, in the prevention of oxidative damage and as an anti-microbial agent.
Trade Name: Shaanxi Huatai Bio-fine Chemical Co.,Ltd.
Common Name: Glabridin
Chemical Name : 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]-1,3-benzenediol
CAS No.: 59870-68-7
EINECS No.: 611-908-7
Molecular Formula: C20H20O4
Characteristics: Reddish brown powder
Solubility: Dissolved in ethanol, 1,3-butanediol. Do not dissolved in water
Specification: Cosmetic grade
Category: Skin Care
Functions: Skin whitening agent
Features: Glabridin is a chemical compound that is found in the root extract of licorice (Glycyrrhiza glabra). Glabridin is an isoflavane, a type of isoflavonoid. This product is part of a larger family of plant-derived molecules, the natural phenols.
It is used as an ingredient in cosmetics and is listed in International Nomenclature of Cosmetic Ingredients (INCI).
Applications: skin care products, oil control cosmetics, anti-acne cosmetics
Typical Dosage: 1‰-5‰
Packing: 1kg aluminum foil bag
Transport: Non-hazardous cargo(IMO/IATA)
Remarks: Safety and efficacy report available upon request.
Product feature application
1. Skin Whitening, Lightening and anti-freckle. Glabridin helps in the inhibition of tyrosinase, dopachrome，tautomerase and activity of DHICA oxidation enzyme, endothelin。
2.Anti-Inflammation. By inhibiting cydooxygenna-2 （COX-2）, glabridin helps to reduce the inflammation.
3. Anti-Oxidant & Anti-free radical. Glabridin helps in the reduction of reactive oxygen.
Under UV stimulation, inhibition of melanin in the 3D bioartificial skin model, from left to right as shown in control group, UVB group, glabridin group, kojic acid group
Under UV stimulation, sedimentation of melanin in the 3D bioartificial skin model, from left to right as shown in control group, UVB group, glabridin group, kojic acid group
Tyrosinase Activity Inhibition Comparision: Anti-tyrosinase activity of Glabridin compare with the other brightening ingredients.
Effects of Glabridin 40% and other whitening active ingredients on 0.5mg of L-tyrosineand 4mg of tyrosinase 24 hr.
1. 1kg with double plastic container inside/Aluminum foil bag outside.
2. 25kg with double plastic container inside/Fiber drum outside.
3. The final decision will be made by your company.