Milk Thistle Extract

Milk Thistle Extract

● Antioxidant
● Inhibition NO
● Promote hepatocyte repair


Introduction for Milk Thistle Extract

Silybum marianum Gaertn is a plant of the genus Asteraceae, which is used in the whole plant and achenes. Whole grass is used for swelling and erysipelas; fruit and extract are used for liver disease, spleen gallstone, jaundice and chronic cough. Clearing away heat and detoxification, has good curative effect on liver and biliary inflammatory diseases such as acute or chronic hepatitis, cirrhosis, fatty liver, metabolic toxic liver injury, cholelithiasis, cholangitis and perihepatitis, and can make patients with liver disease feel symptoms and Some biochemical indexes such as serum bilirubin, ferrets and globule coefficients, thrombin, alanine aminotransferase, etc., are rapidly improving.

Milk Thistle is warm and sunny, and adaptable. Cold, drought and high temperature. The seedlings can withstand low temperatures around 0 °C, suitable for cold planting, strong seed germination, and can land on their own. The suitable temperature for seed germination is 15 ° C ~ 25 ° C, the soil moisture requirements are not strict, beach land, saline land can be planted. It should be cultivated in well-drained sandy soil.

Main Function

Milk Thistle Extract has been used as a natural botanical drug for the treatment of hepatobiliary diseases. In 1952, the Beijing Botanical Garden was introduced from the United Kingdom for ornamental plant cultivation. In 1972, the Tianjin Native Produce Branch of the Chinese Native Produce and Animal Products Import and Export Corporation was introduced from Germany as a medicinal plant. Milk Thistle Extract contains a flavonoid complex called silymarin. This substance is the main source of the medicinal value of the plant. Milk Thistle Extract is composed of three isomers: silybin, silibinin, and silyin.

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Main effects:

Antioxidant effects: Milk Thistle Extract and reactive oxygen species (ROS) are highly reactive, can cause lipid peroxidation with unsaturated fatty acids, damage cell membranes, and can cause chromosome aberrations. The study found that silymarin significantly inhibited the production of ROS by human neutrophils and was dose-related.

Inhibition of NO production: In pathological conditions such as cirrhosis, excessive NO production can cause high-power circulation and hypoxemia. In addition, NO also has a cytotoxic effect that enhances the toxicity of activated mononuclear macrophages. Milk Thistle Extract inhibits the production of NO by activated Kupffer cells, which in turn weakens the interaction between NO and O2-, and its mechanism may be similar to scavenging free radicals.

Promote hepatocyte repair: Milk Thistle Extract can be completely inhibited by the formation of malondialdehyde and chemical luminescence after it enters hepatocytes. Milk Thistle Extract itself binds to and activates the estradiol receptor, which enhances the function of the hepatocyte nucleus as a free radical scavenger, particularly enhances the activity of RNA polymerase, enhances the transcription of ribosomal RNA (rRNA), and cytoplasmic ribose The increase in the number of organisms promotes the synthesis of enzymes and structural proteins, and indirectly promotes DNA synthesis in cells, which is beneficial to the repair and regeneration of hepatocytes.


Carton: 1kg with double plastic container inside/Aluminum foil bag outside; 

25kg with double plastic container inside/Fiber drum outside.

or as customer’s requirement.

Drum: 10kg,15kg,25kg




Shipping Terms

By express

By Air

By Sea

Suitable for ≤50kgs


High cost

Door to Door

Easy Pick Up Goods

Suitable for ≥50kgs


High Cost

Airport to Airport

Pick Up Goods by Customer

Suitable for ≥500kgs


Low Cost

Port to Port

Pick Up Goods by Customer

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Payment Terms

Western Union

Money Gram


Bank Transfer

Finishing workshop

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