Introduction for Glabridin powder
Licorice is the dry root and rhizome of leguminous ural licorice, licorice or licorice, containing licorice flavonoids and glycyrrhizic acid, glycyrrhetinic acid, glycyrrhizic acid diamine, glycyrrhizin, glycyrrhizin, glycyrrhizin, A variety of biologically active ingredients such as isoglycyrrhizin are mainly distributed in western China and Central Asia. In recent years, there have been many studies on the flavonoids of licorice. Glycyrrhiza glabra L. is an important component in the flavonoid bioactive substances of licorice. It is only found in the roots of Glycyrrhiza glabra. It is the most important isoflavone component in Glycyrrhiza glabra. It accounts for 11. 0 %.
Glabridin powder is stable at room temperature, not only has important clinical pharmacological effects such as blood fat lowering, blood pressure lowering and cardiovascular disease prevention, but also has certain value in skin anti-oxidation and whitening and freckle, in skin health beauty and cosmetics. The industry has received much attention and is widely used. Studies have shown that Glabridin powder can reduce the activity of T1 and T3 tyrosinase isoenzymes in B16 murine melanoma cells, and has recently been confirmed by some unit application studies and clinical efficacy, and has developed high-grade whitening cosmetics to promote the market. Due to the water-insoluble and special physical and chemical properties of Glycyrrhiza glabra L. and the unique barrier function of human skin tissue structure, transdermal penetration and active absorption are significantly affected and restricted, which greatly reduces the light licorice itself. Biological effects and clinical efficacy.
The effects of different factors on the encapsulation efficiency and particle size of liposomes at different levels were investigated by the ratio of lecithin to cholesterol, the concentration of Glabridin powder-propylene glycol solution and the time of ultrasonic emulsification. The results showed that when the mass ratio of lecithin to cholesterol was 5:1, the drug encapsulation efficiency reached 80. 0%, when the mass ratio of lecithin to cholesterol is 3:1, the drug encapsulation efficiency is 70. 0%, so the mass ratio of lecithin to cholesterol is controlled at 3:1 to 5:1, and the encapsulation efficiency is better.
The light-grass was used as the raw material to prepare the liposomes of glabridin powder by complex coacervation method. The content of licorice was determined by high performance liquid chromatography. The encapsulation efficiency and particle size were used as indicators to optimize the lipids of licorice by orthogonal test. The preparation process of the body. The results showed that the optimal conditions for the preparation of liposomes were as follows: the ratio of lecithin to cholesterol was 4:1, the time of ultrasonic emulsification was 40 min, and the concentration of glabridin powder-propylene glycol solution was 8 g/L. The liposome particle size distribution is uniform, and the liposome encapsulation efficiency and particle size comprehensive score can be as high as 78 or more, and the particle size is 0. 1 ~ 1. The ratio of 2 μm is 84. 67%.
Carton: 1kg with double plastic container inside/Aluminum foil bag outside;
25kg with double plastic container inside/Fiber drum outside.
or as customer’s requirement.
Suitable for ≤50kgs
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Suitable for ≥50kgs
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Suitable for ≥500kgs
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