Soybean isoflavone is a natural estrogen, a secondary metabolite formed during the growth of soybean, mainly distributed in the seed coat, hypocotyl and cotyledon of soybean. Soybean isoflavone 0.1~0.3g. in every 100g soybean
Soybean isoflavones are polyphenols. In nature, they mainly exist in two forms: free glycosides and conjugated glycosides.
The main effect is three hydroxyl isoflavone, the structural characteristics of the soybean isoflavones and estrogens are similar to estrogen, which can bind to the estrogen receptor and show biological activity.
Prevention and improvement of osteoporosis
Osteoporosis is the reduction of phalangeal tissue, resulting in brittle bones and fragile bones. It is commonly seen in women after menopause and in elderly men (due to hormonal changes or deficiency of calcium and vitamin D). The incidence of osteoporosis in middle-aged and old women is much higher than that of men. The main reason is the decrease of estrogen level after the ovarian function decline, the negative balance of bone metabolism and the decrease of bone mass. Isoflavones can bind to estrogen receptors on bone cells, reduce bone loss, increase body absorption of calcium and increase bone density.
Prevention of breast cancer
Taking estrogen alone for a long time can increase the incidence of breast cancer and endometrial cancer by 5 to 7 times. The structure of soybean isoflavone is similar to that of estrogen, so it can combine the female receptor on the surface of the cell and activate the other anticancer mechanism, which reduces the risk of women with endometrial cancer and breast cancer at the high level of estrogen.
Soybean products contain 5 known anticancer factors, one of which is phytoestrogen (isoflavone), which is the unique anticancer factor of soybean food. Scientists concluded that the antioxidation and genoprotective effect of genistein is the main cause of its anticancer effect. Soybean isoflavones have obvious therapeutic effects on breast cancer, colon cancer, lung cancer, prostate cancer, skin cancer and leukemia, and soybean isoflavones can also prevent the occurrence of ovarian, colon, gastric and prostate cancer.
A large number of studies have found that soy isoflavones can convert cancer cells into normal functioning cells, and also inhibit the structure of bad mass, prevent mass proliferation and cancer cell proliferation.
Prevention of cardiovascular disease
Heart disease is also a disease associated with estrogen. As a plant estrogens, soy isoflavones can reduce blood lipids and prevent heart disease: estrogen like action promotes thyroxine secretion and promotes bile excretion. Lowering cholesterol lowers low density lipoprotein (LDL) cholesterol without reducing the high density lipoprotein (HDL) cholesterol, which has been fully demonstrated. Isoflavones, as a characteristic of flavonoids, have biological antioxidation, which is very important, because the oxidation of low density lipoprotein (LDL) cholesterol is a key factor in the process of arteriosclerosis.
Prevention of Alzheimer's disease
Alzheimer's disease is the most common form of dementia at present. In recent years, studies have shown that the human brain also belongs to the target tissue of estrogen. The hippocampal synaptic body with memory function contains estrogen receptor in the brain. The medical community has confirmed that the level of estrogen is closely related to Alzheimer's disease.
The effect of beauty and delaying senility
The estrogen like effect of soy isoflavones can make women's skin smooth, delicate, tender, elastic and full of youthful charm. The female can activate the fat tissue in the breast by replenishing estrogen, so that free fat can be directed to the breast, so as to achieve the effect of breast enhancement.
The study shows that the phenomenon of advanced menopause in modern women, the long-term supplement of soybean isoflavones can maintain the normal level of estrogen in the body, postpone the menopause and reach the effect of delaying senescence.
Improve menstrual discomfort
The menstrual discomfort is generally related to the imbalance of estrogen secretion. Long term supplementation of soybean isoflavones can maintain the normal level of estrogen in the body and achieve the purpose of improving the discomfort of the menstrual period.
Improving the quality of sexual life
The estrogen like effect of soy isoflavones can increase the maturity of vaginal epithelial cells, enhance the elasticity of vaginal muscles, and improve the quality of sexual life.
Cardiovascular disease (CHD) is a multifactorial disease, of which cholesterol (Ch) plays an important role. A large-scale study conducted by 5000 people in Japan showed that soy isoflavones had the effect of lowering cholesterol Ch and inhibiting thrombosis. In a study of young women in the UK, the dose effect relationship of isoflavones was shown. The total Ch and LDL-Ch levels were reduced by 10% for 30 days after 45 mg of isoflavones, while 23 mg isoflavones did not work.
Regulation of blood lipid
Soybean isoflavones can reduce the body's susceptibility to serum LDL oxidation. The oxidation of LDL lipoprotein in serum activates macrophage phagocytosis in the human body and develops into foam cells in the arterial wall to form atheromatous plaques. Soybean isoflavones not only have their own antioxidant effects, but also induce the increase of antioxidant enzyme activity, increase the antioxidant activity of serum LDL, prevent atherosclerotic plaque formation and prevent atherosclerotic atherosclerosis. At the same time, increase arterial compliance and expand blood vessels. Soy isoflavones also inhibit the process of atherosclerosis by affecting tyrosine kinase, including foam cells, aliphatic veins, hyperplasia, fibrous plaque infiltration, rupture and ulcers, maintaining the unimpeded blood vessels of the heart and preventing the occurrence of cardiovascular disease.
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