Rutin, also called rutoside, quercetin-3-O-rutinoside and sophorin, is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a citrus flavonoid found in a wide variety of plants including citrus fruit.
How does it work?
Rutin has chemicals that might have antioxidant and anti-inflammatory effects. These chemicals might offer some protection against cancer and other diseases.
The ability to bind iron ions is one of the most important biochemical actions of rutin in humans. This action prevents iron ions from forming free radicals by binding with hydrogen peroxide. Free radicals are highly reactive ions that can cause various types of cellular damage. Rutin can also inhibit the production of vascular endothelial growth factor in the laboratory. The most significant benefits of rutin in dietary supplements involve blood vessel health.
Helps blood circulation
Traditionally, rutin has long been used to aid circulation. It’s thought that rutin can help strengthen and increase flexibility in blood vessels, such as your arteries and capillaries.
Strengthened blood vessels can improve your overall health. This may help ease related conditions, including bruises, spider veins, and varicose veins. There is also evidence that rutin can aid in treating hemorrhoids (which are caused by swollen veins) and recovering from hemorrhoid removal surgery.
Prevents blood clots
Research shows that rutin can prevent the formation of blood clots in certain animals. This suggests rutin may reduce the risk of blood clots. Preventing blood clots can help lower your chances of developing life-threatening conditions.
There’s sufficient evidence that rutin can help lower LDL cholesterol. In one study, people with diabetes who had a history of hypertension were given 500 milligrams (mg) of rutin once a day. Researchers found a decrease in the plasma LDL cholesterol levels of participants. The study suggests that this is a result of rutin’s antioxidant properties.
Reduces arthritis pain
One of rutin’s common uses is to ease arthritis pain. A study found that it aided in suppressing oxidative stress in people with arthritis. This may be due to rutin’s strong anti-inflammatory and antioxidant properties. There’s also evidence that rutin improves knee function in some who have arthritis.
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