● CAS: 520-26-3
● Melting point: 250-255 C
● Molecular formula: C28H34O15
● Storage conditions: 2-8 C
● Molecular weight: 610.56


citrus extract powder.jpgHesperidin is a flavan-on glycoside found in citrus fruits. Its aglycone form is called hesperetin. Citrus fruits, mainly oranges and tangerines, contain hesperidin .Its name is derived from the word "hesperidium", for fruit produced by citrus trees.Hesperidin is a bioflavonoid glycoside. Hesperidin was first isolated in 1828 by French chemist Lebreton from the white inner layer of citrus peels (mesocarp, albedo).


Physical properties

slightly soluble in methanol and hot glacial acetic acid, almost insoluble in acetone, benzene and chloroform, but soluble in dilute alkali and pyridine.




Oxidants, such as hydrogen peroxide and other chemicals, cause oxidative stress. Oxidative damage causes disorders such as cancer and heart disease. Antioxidants help protect against oxidative stress.

Both hesperidin and hesperitin function as antioxidants. They both have radical scavenging activity. This means that they stop free radicals from damaging cells.Hesperidin had significant radical scavenging activity in red blood cells. It stopped hydrogen peroxide from damaging the cellular membranes of blood cells. It also protected against DNA damage.


Inflammatory mediators include iNOS and COX-2 and inflammatory cytokines.Hesperidin and its metabolites lower inflammation. In cellular models of inflammation, hesperidin administration suppressed iNOS protein levels and COX-2 enzyme levels.It also reduced inflammatory cytokine production.

Fat Loss

Hesperidin may increase adiponectin, a protein hormone that helps control glucose and fat energy production. Increasing adiponectin helps reduce fat accumulation. This helps to prevent obesity.Hesperidin and p-synephrine (part of bitter orange extract) also increase the metabolic rate. The metabolic rate is the rate at which the body burns calories.

Treat Allergies

Immunoglobulin E (IgE) provokes allergic reactions by releasing histamine and causing inflammation. In humans, administration of both hesperidin and hesperitin suppressed IgE’s effects. It inhibited histamine release and stopped Th2 cytokine secretion.

Skin Health

Additionally, hesperidin protects the skin from radiation. A compound called hesperidin methyl chalcone helped stop oxidative damage in skin cells. It reduced free radicals and reduced inflammatory cytokine production.Topical hesperetin may also be an effective skin whitening agent.


Hesperidin administration enhances osteoblast formation. Osteoblasts are cells that help with bone formation.

Hesperitin-7-glucuronide is the main circulating form of hesperidin. Its administration in rats helped increase bone cell formation.

Hesperidin may improve bone energy proudction. It prevents bone loss caused by estrogen deficiency.


Carton: 1kg with double plastic container inside/Aluminum foil bag outside; 

25kg with double plastic container inside/Fiber drum outside.

or as customer’s requirement.

Drum: 10kg,15kg,25kg




Shipping Terms

By express

By Air

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Suitable for ≤50kgs


High cost

Door to Door

Easy Pick Up Goods

Suitable for ≥50kgs


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Airport to Airport

Pick Up Goods by Customer

Suitable for ≥500kgs


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Port to Port

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Payment Terms

Western Union

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Finishing workshop

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