Enoxolone from glycyrrhetic acid for reduce inflammation and dephlogisticate
Enoxolone, also known as glycyrrhetinic acid or glycyrrhetic acid, is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb licorice. It is used in flavoring and it masks the bitter taste of drugs like aloe and quinine. It is effective in the treatment of peptic ulcer and also has expectorant (antitussive) properties. It has some additional pharmacological properties including antiviral, antifungal, antiprotozoal, and antibacterial activities
Trade Name: Shaanxi Huatai Bio-fine Chemical Co., Ltd.
Common Name: Enoxolone
Chemical Name: 18-beta-Glycyrrhetinic acid;
CAS No.: 471-53-4
EINECS No.: 207-444-6
Molecular Formula: C30H46O4
Characteristics: White powder
Solubility: Dissolved in ethanol, 1,3-butanediol. Do not dissolved in water
Specification: Cosmetic grade
Functions: Antioxidant, anti-virus, estrogen-like effects
Typical Dosage: 1‰-5‰
Packing: 1kg aluminum foil bag
Transport: Non-hazardous cargo(IMO/IATA)
Remarks: Safety and efficacy report available upon request.
Product feature application
0.3mmol / L Enoxolone had obvious scavenging effect on the oxygen free radicals released by human polymorphonuclear leukocytes (PMN), but had no effect on PMN oxygen consumption. Enoxolone has obvious scavenging effect on O-2 and -OH produced by aqueous solution system. 30mol / L of PMN produced by the chemiluminescence significantly inhibited. The results confirmed Enoxolone has a direct capture of oxygen free radicals.
The structure of Enoxolone is similar to that of cortisone. Both molecules are flat and similar at position 3 and 11. This might be the basis for licorice's anti-inflammatory action.
Deliver, shipping and serving
Applications: Widely used in cosmetic product as cream, paste, water solution and emulsion.
1. 1kg with double plastic container inside/Aluminum foil bag outside.
2. 25kg with double plastic container inside/Fiber drum outside.
3. The final decision will be made by your company.