Berberine is an important alkaloid. It has been used for a long time in China. A main alkaloid contained in rhizome of Rhizoma of Ranunculus, can be extracted from Coptis chinensis, Phellodendron chinense or three needles, and can also be synthesized artificially. It has significant bacteriostasis. Berberine hydrochloride is also called berberine, which is commonly used as berberine hydrochloride. Berberine can antagonize the pathogenic microorganism, and can inhibit a variety of bacteria such as bacillary bacilli, Mycobacterium tuberculosis, pneumococcus, typhus and diphtheria, which have the strongest effect on bacillary bacilli. It is often used to treat digestive tract diseases such as bacterial gastroenteritis and dysentery. It is mainly used for the treatment of bacillary dysentery and gastroenteritis. Its side effects are small.
Antiviral action of microorganism
Antibacterial action: antiviral effect; antigen worm; antiviral action.
The role of the cardiovascular system
Antiarrhythmic, lower blood pressure, positive inotropic; clinical reports berberine has protective effects on ischemic brain damage.
The pharmacological and clinical studies of the hypoglycemic effect have proved that berberine not only has significant hypoglycemic effect, but also has a good preventive effect on the complication of diabetes patients with complication of hypertension.Berberine is an over-the-counter drug for the treatment of bacterial diarrhea. Many doctors in China have used it for diabetes treatment and achieved good results.
Many studies have shown that dysfunctional intestinal flora may cause endotoxin into blood, induce chronic inflammation, and cause metabolic diseases such as obesity, diabetes, coronary heart disease and so on. Berberine can improve the structure of intestinal flora, reduce endotoxin into blood and reduce chronic inflammation, so as to achieve the purpose of treatment or prevention of diabetes.
Regulation of blood lipid
Berberine is in the post transcriptional level, by acting on the 3'UTR region to stabilize the low density lipoprotein receptor mRNA (messenger ribonucleic acid) to reduce blood lipids, and the mechanism of the use of statins is completely different.
It can obviously enhance the activity of liver superoxide dismutase, reduce the level of liver lipid peroxidation and the content of serum three acylglycerol and total cholesterol. It has a good effect on the prevention and treatment of obesity, fatty liver and arteriosclerosis.
Inhibition of platelet aggregation.
Enhance the immune function.
Anti ulcer effect; antipyretic effect; Coptis also has central inhibition and gallbladder effect.
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