The extraction methods of chlorogenic acid include water extraction, alcohol precipitation, alcohol extraction, lead precipitation and lime milk precipitation. It contains 5 hydroxyl groups and 1 carboxyl groups, resulting in a solubility of 4% in water.
Chlorogenic acid has a wide range of biological activities. The study of the bioactivity of chlorogenic acid in modern science has penetrated into many fields, such as food, health care, medicine and daily chemical industry. It is an important biological active substance, which has the functions of antibacterial, antiviral, increasing white blood cells, protecting liver and gallbladder, anti tumor, lowering blood pressure, lowering blood fat, clear free radical and excited seed tree nerve system.
Antivirus and antiviral
The chlorogenic acid of Eucommia ulmoides Oliv has strong anti-inflammatory and anti-inflammatory effects, and the anthocyanins and their polymers have obvious bacteriostasis, and the anthocyanins have inhibitory effect on Gram-negative and positive bacteria. The anthocyanins have bacteriostasis, diuretic effect and can promote the healing of the wound. In combination with glucoside and glucoside, the anthocyanin can produce obvious antiviral effect, but it does not have the antiviral function itself.
Chlorogenic acid is an effective phenolic antioxidant, and its antioxidant capacity is stronger than caffeic acid, para hydroxybenzoic acid, ferulic acid, syringic acid, butyl hydroxy anisole and tocopherol. The reason that chlorogenic acid has the antioxidant effect is that it contains a certain amount of R-OH base and can form a hydrogen radical with antioxidant effect to eliminate the activity of free radicals such as hydroxyl radical and superoxide anion, thus protecting tissue from oxidative damage.
Inhibition of mutation and antitumor
Modern pharmacological experiments have proved that chlorogenic acid in Eucommia ulmoides has the effect of anticancer and cancer suppression. Japanese scholars have studied the antigenicity of chlorogenic acid in Eucommia ulmoides, and found that this effect is related to the antiantogenic components of chlorogenic acid, and explains the significance of chlorogenic acid in the prevention of cancer.
Protective effect on cardiovascular
Chlorogenic acid, a free radical scavenger and antioxidant, has been proved by a large number of experiments. The bioactivity of chlorogenic acid can protect the cardiovascular system.
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